Eating disorders neuroscience in youth theme

The Ravello Profile - neuropsychological assessment in eating disorders (Dr. Ian Frampton, Professor Huw Williams, Professor Emeritus Bryan Lask, Marie-Claire Reville)

This international collaborative research project aims to develop a standard neuropsychological assessment for research and clinical use in eating disorders. Participating centres from Europe, Scandinavia, North and South America have established a joint database to help us understand more about the neuropsychological consequences (and potential causes) of eating disorders. Generous funding by the Rosetree's Trust, Care UK, the Huntercombe Group, the Ellern Mede Centre for Eating Disorders and Helse Sør Øst, Norway has supported this project. For further details, see www.ravelloprofile.org.

Functional neuroimaging in eating disorders (Dr. Ian Frampton, Professor Huw Williams, Professor Emeritus Bryan Lask, Marie-Claire Reville)

Our studies in this area are exploring how brain function is affected by starvation during the acute phase of eating disorders, and also testing our noradrenergic hypothesis (Nunn et al, 2012) that dysfunction of a neural network incorporating the insula cortex in the brain could be an underlying risk factor. With the support of Helse Sør Øst, Norway (www.rasp.no) and colleagues from the Centre for Neuroimaging Sciences at the University of London (www.neuroimagingsciences.com), we have developed and tested a novel hypothesis using functional neuroimaging techniques. We are now developing our research into potential neuroscience-based treatments for eating disorders in collaboration with the Exeter MR Research Centre (centres.exeter.ac.uk/pmrrc/).