Publications by category
Journal articles
Hardy L, Hogarth L (In Press). A novel concurrent pictorial choice model of mood-induced relapse in hazardous drinkers. Experimental and clinical psychopharmacology
Hardy L, Josephy K, McAndrew A, Hawksley P, Hartley L, Hogarth L (2019). Evaluation of the Peninsula Alcohol and Violence Programme (PAVP) with violent offenders.
ADDICTION RESEARCH & THEORY,
27(2), 122-129.
Author URL.
Hogarth L, Hardy L, Bakou A, Mahlberg J, Weidemann G, Cashel S, Moustafa AA (2019). Negative Mood Induction Increases Choice of Heroin Versus Food Pictures in Opiate-Dependent Individuals: Correlation with Self-Medication Coping Motives and Subjective Reactivity.
FRONTIERS IN PSYCHIATRY,
10 Author URL.
Hogarth L (2018). A concurrent pictorial drug choice task marks multiple risk factors in treatment-engaged smokers and drinkers. Behavioural Pharmacology
Hogarth L (2018). Alcohol use disorder symptoms are associated with greater relative value ascribed to alcohol, but not greater discounting of costs imposed on alcohol. Psychopharmacology
Hogarth L, Hardy L, Mathew AR, Hitsman B (2018). Negative mood-induced alcohol-seeking is greater in young adults who report depression symptoms, drinking to cope, and subjective reactivity.
Experimental and Clinical Psychopharmacology,
26(2), 138-146.
Abstract:
Negative mood-induced alcohol-seeking is greater in young adults who report depression symptoms, drinking to cope, and subjective reactivity
Acute negative mood powerfully motivates alcohol-seeking behavior, but it remains unclear whether sensitivity to this effect is greater in drinkers who report depression symptoms, drinking to cope, and subjective reactivity. To examine these questions, 128 young adult alcohol drinkers (ages 18-25) completed questionnaires of alcohol use disorder symptoms, depression symptoms, and drinking to cope with negative affect. Baseline alcohol choice was measured by preference to enlarge alcohol versus food thumbnail images in two-alternative forced-choice trials. Negative mood was then induced by depressive statements and music, before alcohol choice was tested. Subjective reactivity was indexed by increased sadness pre- to post-mood induction. Baseline alcohol choice correlated with alcohol dependence symptoms (p <. 001), and drinking coping motives (ps ≤. 01). Mood induction increased alcohol choice and subjective sadness overall (ps <. 001). The mood-induced increase in alcohol choice was associated with depression symptoms (p =. 007), drinking to cope (ps ≤. 03), and subjective reactivity (p =. 007). The relationship between mood-induced alcohol choice and drinking to cope remained significant after covarying for other drinking motives. Furthermore, the three predictors (depression, drinking to cope, and subjective reactivity) accounted for unique variance in mood-induced alcohol choice (ps ≥. 03), and collectively accounted for 18% of the variance (p <. 001). These findings validate the pictorial alcohol choice task as sensitive to the relative value of alcohol and acute negative mood. The findings also accord with the core prediction of negative reinforcement theory that sensitivity to the motivational impact of negative mood on alcohol-seeking behavior may be an important mechanism that links depression and alcohol dependence.
Abstract.
Hogarth L, Hardy L (2017). Depressive statements prime goal-directed alcohol-seeking in individuals who report drinking to cope with negative affect. Psychopharmacology, 235, 269-279.
Hardy L, Mitchell C, Seabrooke T, Hogarth L (2017). Drug cue reactivity involves hierarchical instrumental learning: evidence from a biconditional Pavlovian to instrumental transfer task.
Psychopharmacology (Berl),
234(13), 1977-1984.
Abstract:
Drug cue reactivity involves hierarchical instrumental learning: evidence from a biconditional Pavlovian to instrumental transfer task.
RATIONALE: Drug cue reactivity plays a crucial role in addiction, yet the underlying mechanisms are poorly understood. According to the binary associative account, drug stimuli retrieve an expectation of the drug outcome, which, in turn, elicits the associated drug-seeking response (S-O-R). By contrast, according to the hierarchical account, drug stimuli retrieve an expectation that the contingency between the drug-seeking response and the drug outcome is currently more effective, promoting performance of the drug-seeking response (S:R-O). METHODS: the current study discriminated between these two accounts using a biconditional Pavlovian-to-instrumental transfer (PIT) task with 128 alcohol drinkers. A biconditional discrimination was first trained in which two responses produced alcohol and food outcomes, respectively, and these response-outcome contingencies were reversed across two discriminative stimuli (SDs). In the PIT test, alcohol and food cues were compounded with the two SDs to examine their impact on percent alcohol choice in extinction. RESULTS: it was found that alcohol and food cues selectively primed choice of the response that earned that outcome in each SD (p
Abstract.
Author URL.
Publications by year
In Press
Hardy L, Hogarth L (In Press). A novel concurrent pictorial choice model of mood-induced relapse in hazardous drinkers. Experimental and clinical psychopharmacology
2019
Hardy L, Josephy K, McAndrew A, Hawksley P, Hartley L, Hogarth L (2019). Evaluation of the Peninsula Alcohol and Violence Programme (PAVP) with violent offenders.
ADDICTION RESEARCH & THEORY,
27(2), 122-129.
Author URL.
Hogarth L, Hardy L, Bakou A, Mahlberg J, Weidemann G, Cashel S, Moustafa AA (2019). Negative Mood Induction Increases Choice of Heroin Versus Food Pictures in Opiate-Dependent Individuals: Correlation with Self-Medication Coping Motives and Subjective Reactivity.
FRONTIERS IN PSYCHIATRY,
10 Author URL.
2018
Hogarth L (2018). A concurrent pictorial drug choice task marks multiple risk factors in treatment-engaged smokers and drinkers. Behavioural Pharmacology
Hogarth L (2018). Alcohol use disorder symptoms are associated with greater relative value ascribed to alcohol, but not greater discounting of costs imposed on alcohol. Psychopharmacology
Hogarth L, Hardy L, Mathew AR, Hitsman B (2018). Negative mood-induced alcohol-seeking is greater in young adults who report depression symptoms, drinking to cope, and subjective reactivity.
Experimental and Clinical Psychopharmacology,
26(2), 138-146.
Abstract:
Negative mood-induced alcohol-seeking is greater in young adults who report depression symptoms, drinking to cope, and subjective reactivity
Acute negative mood powerfully motivates alcohol-seeking behavior, but it remains unclear whether sensitivity to this effect is greater in drinkers who report depression symptoms, drinking to cope, and subjective reactivity. To examine these questions, 128 young adult alcohol drinkers (ages 18-25) completed questionnaires of alcohol use disorder symptoms, depression symptoms, and drinking to cope with negative affect. Baseline alcohol choice was measured by preference to enlarge alcohol versus food thumbnail images in two-alternative forced-choice trials. Negative mood was then induced by depressive statements and music, before alcohol choice was tested. Subjective reactivity was indexed by increased sadness pre- to post-mood induction. Baseline alcohol choice correlated with alcohol dependence symptoms (p <. 001), and drinking coping motives (ps ≤. 01). Mood induction increased alcohol choice and subjective sadness overall (ps <. 001). The mood-induced increase in alcohol choice was associated with depression symptoms (p =. 007), drinking to cope (ps ≤. 03), and subjective reactivity (p =. 007). The relationship between mood-induced alcohol choice and drinking to cope remained significant after covarying for other drinking motives. Furthermore, the three predictors (depression, drinking to cope, and subjective reactivity) accounted for unique variance in mood-induced alcohol choice (ps ≥. 03), and collectively accounted for 18% of the variance (p <. 001). These findings validate the pictorial alcohol choice task as sensitive to the relative value of alcohol and acute negative mood. The findings also accord with the core prediction of negative reinforcement theory that sensitivity to the motivational impact of negative mood on alcohol-seeking behavior may be an important mechanism that links depression and alcohol dependence.
Abstract.
2017
Hogarth L, Hardy L (2017). Depressive statements prime goal-directed alcohol-seeking in individuals who report drinking to cope with negative affect. Psychopharmacology, 235, 269-279.
Hardy L, Mitchell C, Seabrooke T, Hogarth L (2017). Drug cue reactivity involves hierarchical instrumental learning: evidence from a biconditional Pavlovian to instrumental transfer task.
Psychopharmacology (Berl),
234(13), 1977-1984.
Abstract:
Drug cue reactivity involves hierarchical instrumental learning: evidence from a biconditional Pavlovian to instrumental transfer task.
RATIONALE: Drug cue reactivity plays a crucial role in addiction, yet the underlying mechanisms are poorly understood. According to the binary associative account, drug stimuli retrieve an expectation of the drug outcome, which, in turn, elicits the associated drug-seeking response (S-O-R). By contrast, according to the hierarchical account, drug stimuli retrieve an expectation that the contingency between the drug-seeking response and the drug outcome is currently more effective, promoting performance of the drug-seeking response (S:R-O). METHODS: the current study discriminated between these two accounts using a biconditional Pavlovian-to-instrumental transfer (PIT) task with 128 alcohol drinkers. A biconditional discrimination was first trained in which two responses produced alcohol and food outcomes, respectively, and these response-outcome contingencies were reversed across two discriminative stimuli (SDs). In the PIT test, alcohol and food cues were compounded with the two SDs to examine their impact on percent alcohol choice in extinction. RESULTS: it was found that alcohol and food cues selectively primed choice of the response that earned that outcome in each SD (p
Abstract.
Author URL.
