Skip to main content

profile

Loading content
Dr Lee Hogarth

Dr Lee Hogarth

Associate Professor

 4613

 Washington Singer 232

 

Washington Singer Laboratories, University of Exeter, Perry Road, Prince of Wales Road, Exeter, EX4 4QG, UK

 Office hours:

UG office hours: Mondays 2-3 (via MS Teams) and Wednesday 11:30-12:30 (in office)

Overview

Lee Hogarth is an experimental health psychologist with a core focus on risk factors and treatment mechanisms in addiction. His work encompasses epidemiology combined with experimental manipulation of risk factors to test causal effects, small scale randomised controlled trials evaluating therapeutic ingredients, secondary data analysis, and critical evaluation of animal to human translational pipelines and grand theoretical models of addiction. He is a critic of the brain disease model and related automaticity and compulsion theories of addiction, arguing that attributing addiction to individuals’ personal flaws further marginalises already disadvantaged groups and is a form of victim blaming veiled in scientific language. Instead, he argues that addiction arises from economic/environmental deprivation motivating abnormal intentional drug choice. He advocates structural/political reform promoting access to healthy, rewarding, and exciting alternatives.

Qualifications

BSc Hons 1st, Sussex,
PhD, Cambridge

Career

I received my PhD from Cambridge University in 2000 for research on conditioning processes in human addiction supervised by Prof Anthony Dickinson. I then obtained two grants (Wellcome, BBSRC) supporting 7 years of postdoctoral research on attentional learning at Sussex University with Prof Theodora Duka. I obtained a lectureship at Nottingham University in 2007 and shortly after was awarded an MRC young investigators award for 3 years of research on individual differences in associative learning underlying addiction vulnerability. I took up a Senior Lectureship at the University of New South Wales (UNSW), Australia, in 2012, under the academic lead of Prof Simon Killcross. Finally, I returned home in 2013 to take up an Associate Professorship at Exeter University under the academic lead of Prof. Ian McLaren.

Links

Research group links

Research

Research interests

I am an associate professor in the Department of Psychology at the University of Exeter UK. My work focuses on individual risk factors, pathways and mechanisms that confer risk of transitioning from recreational substance use to dependence, protective factors that reduce risk by diverting vulnerable groups, and mechanisms that mediate recovery from addiction. My work has been funded by the Wellcome Trust, BBSRC, ESRC, MRC and Alcohol Change UK. At the start of my career, I focused on translating animal associative learning theory and behavioral neuroscience methods to humans to test whether vulnerability mechanisms found in animals were also found in humans. My PhD and early post-doctoral work tested the prediction of incentive salience theory that drug related cues command selective attention which controls automatic drug-seeking. I developed conditioning procedures to measure acquired attentional bias for drug paired cues with eye tracking. However, this learned attentional bias was not reliably associated with level of dependence severity and could be abolished without affecting the capacity of drug stimuli to elicit drug-seeking behavior suggesting the attentional bias for drug cues does not underpin dependence vulnerability and is not a viable target for treatment. Consequently, I moved on to test cue reactivity theory which claims that dependence liability is conferred by greater sensitivity to drug cue priming of drug-seeking behavior. For this purpose, I was first person to develop a human Pavlovian to instrumental transfer procedure with drug rewards, translating method in animal behavioral neuroscience. However, there was no evidence that dependence was associated with greater capacity of drug cues to prime drug-seeking behavior above baseline, so cue reactivity could not underpin individual vulnerability to dependence, contrary to this widely held assumption (Hogarth, 2022). I then returned to test the preferred hypothesis of my one-time PhD supervisor, Anthony Dickinson (FRS) – that drug dependence is driven by excessive habit learning, that is, the tendency to engage in well-practiced drug-seeking behavior without forethought for the consequences. For this purpose, I was the first person to develop an outcome-devaluation procedure for humans with drug reinforcers. However, once again, the predictions of animal behavioral neuroscience failed to translate to humans – I consistently found no evidence that variation in human dependence severity was associated with greater habit learning. I have since positioned myself as a vocal critic of habit theory of addition, on the grounds that habit effects in animals occur in such narrow experimental conditions that this effect lacks ecological validity for humans. Moreover, the minority of human studies which do report greater habit learning in drug users are flawed because the users also report greater disengagement from the tasks (reduced task contingency knowledge), suggesting the observed impairment in performance does not stem form habit learning, but from a trivial, non-specific reduction in task motivation. My recent critical review of habit theory won the journal of Neuropsychopharmacology’s NEAR award at the 2021 ACNP meeting in Puerto Rico (Hogarth, 2020).

 

My most recent findings suggest that dependence liability can be attributed to preferential goal-directed drug choice governed by greater expected value of the drug in vulnerable individuals (Hogarth & Field, 2020). Across 23 studies, the average correlation between preferential goal-directed drug choice and dependence severity was r=0.51, suggesting this mechanism can account for 26% of the variance in dependence severity (probably the most reliable behavioral marker yet published). Additionally, experimentally induced adverse states (negative mood and stress) motivate further goal-directed drug choice above the baseline preference, and this negative induction effect is powerful enough to overrule the reduction in drug choice produced by devaluation through specific satiety. This powerful effect suggests that negatively motivated goal-directed drug choice could explain the persistence of drug-seeking despite harms/costs. Most importantly, individuals who self-report using substances to cope with negative affect are reliably more susceptible to negatively motivated goal-directed drug choice in laboratory paradigms. Given that self-reported coping motives mediate the greater risk of dependence in individuals who have experienced poverty, discrimination, bullying, adverse childhood events, trauma, and mental health problems, it can be argued that susceptibility to negatively motivated goal-directed drug choice underpins the greater risk of addiction seen in these vulnerable groups. Regarding interventions, whereas the automatic, habit, and compulsion theories of addiction inspire biomedical interventions to correct supposed constitutional learning abnormalities, the negatively motivated goal-directed account inspires interventions that target coping motives as well as systemic reforms to reduce adversity in disadvantaged groups, fitting with a social justice agenda which I find personally rewarding (Hogarth, 2022; Shuai et al., 2022).

 

Hogarth, L. (2020). Addiction is driven by excessive goal-directed drug choice under negative affect: translational critique of habit and compulsion theory. Neuropsychopharmacology, 45(5), 720-735. https://doi.org/10.1038/s41386-020-0600-8

Hogarth, L. (2022). The persistence of addiction is better explained by socioeconomic deprivation related factors powerfully motivating goal-directed drug choice than by automaticity, habit or compulsion theories favored by the brain disease model. In N. Heather, M. Field, A. Moss, & S. Satel (Eds.), Evaluating the Brain Disease Model of Addiction. Routledge.

Hogarth, L., & Field, M. (2020). Relative expected value of drugs versus competing rewards underpins vulnerability to and recovery from addiction. Behavioural Brain Research, 394, 112815. https://doi.org/10.1016/j.bbr.2020.112815

Shuai, R., Anker, J. J., Bravo, A. J., Kushner, M. G., & Hogarth, L. (2022). Risk pathways contributing to the alcohol harm paradox: Socioeconomic deprivation confers susceptibility to alcohol dependence via greater exposure to aversive experience, internalizing symptoms and drinking to cope [Original Research]. Frontiers in Behavioral Neuroscience, 16https://doi.org/10.3389/fnbeh.2022.821693

 

Contributions to Science 

1. Incentive salience theory of addiction in humans

My PhD and early Postdoctoral research tested Robinson and Berridge’s (1993) incentive salience theory of addiction in humans. This account predicts that (a) drug addicts should have their attention captured by drug cues, (b) attentional capture by drug cues should play a causal role in driving drug-seeking behavior, and therefore (c) abolishing the attentional bias should reduce cue-elicited drug-seeking. My first publication was one of the earliest demonstrations that drug cues do in fact capture addicts’ attention, using a reaction time measure of attention(A) and is in the top 10% for citations relative to comparable articles based on Scopus data. My subsequent work demonstrated that this attentional bias could be conditioned to arbitrary stimuli and measured more sensitively by eye tracking(B). However, I later discovered that abolishing the attentional bias did not reduce the ability of drug cues to elicit drug-seeking behavior, suggesting that abolishing the attentional bias will not provide a viable therapeutic intervention for addiction(C,D). This latter paper is in the top 30% for citations despite contradicting a core tenet within addiction theory. My prediction from this pre-clinical work, that attentional bias retraining would not yield therapeutic benefits, has been confirmed by clinical trials.

A. Hogarth LC, Mogg K, Bradley BP, Duka T, Dickinson A. Attentional orienting towards smoking-related stimuli. Behav Pharmacol. 2003 Mar;14(2):153-60. PMID: 12658076.

B. Hogarth L, Dickinson A, Hutton SB, Elbers N, Duka T. Drug expectancy is necessary for stimulus control of human attention, instrumental drug-seeking behaviour and subjective pleasure. Psychopharmacology (Berl). 2006 May;185(4):495-504. PMID: 16547713.

C. Hogarth L, Dickinson A, Janowski M, Nikitina A, Duka T. The role of attentional bias in mediating human drug-seeking behaviour. Psychopharmacology (Berl). 2008 Nov;201(1):29-41. PMID: 18679657.

D. Hogarth L, Dickinson A, Duka T. Detection versus sustained attention to drug cues have dissociable roles in mediating drug seeking behavior. Exp Clin Psychopharmacol. 2009 Feb;17(1):21-30. PMID: 19186931.

 

2. Drug cue-reactivity

Having discovered that attentional bias for drug cues is not a viable target for therapy, I switched to studying the decision mechanisms underpinning drug cue-reactivity. My first aim was to test whether cue elicited drug-seeking is automatic as predicted by implicit accounts, or driven by an expectation of the drug as predicted by decision making accounts. To test these predictions, I was the first person to develop an outcome-specific Pavlovian to instrumental transfer (PIT) procedure for humans with drug reinforcers (a method only previously used in animal behavioural neuroscience). My human procedure demonstrated that a drug stimulus could transfer selective control over a separately trained drug-seeking response, but not over a response trained with a different reinforcer(A) (top 6% cited). To produce this effect, the drug stimulus must have retrieved an expectation of the drug which selectively primed drug-seeking. This effect cannot be explained by automatic, habitual or implicit accounts of drug cue-reactivity.

Paradoxically, I later found that the selective control by a tobacco stimulus over a tobacco-seeking response was not attenuated by nicotine replacement therapy (NRT)(B) (top 7% cited). Furthermore, Dr. Hitsman and I extended this result, finding that that cue-elicited tobacco craving was also not attenuated by varenicline(C) (top 25% cited). The implication of these findings is that drug cues elicit drug-seeking by retrieving an expectation that the drug-seeking response has a higher probability of being reinforced, irrespective of whether the drug outcome currently has low value. I subsequently, confirmed this view experimentally and outlined the implications for cue-retraining therapies(D) (top10% cited).

The crucial observation across all of these studies, however, was that the capacity of drug cues to prime drug-seeking in the PIT procedure was not associated with individual differences in level of dependence(A,B,D). Thus, drug cue-reactivity is not the principal mechanism underpinning risk of dependence, so I turned my research program away from this outcome measure.

A. Hogarth L, Dickinson A, Wright A, Kouvaraki M, Duka T. The role of drug expectancy in the control of human drug seeking. J Exp Psychol Anim Behav Process. 2007 Oct;33(4):484-96. PMID: 17924795.

B. Hogarth L. Goal-directed and transfer-cue-elicited drug-seeking are dissociated by pharmacotherapy: evidence for independent additive controllers. J  Exp Psychol Anim Behav Process. 2012 Jul;38(3):266-78. PMID: 22823420.

C. Hitsman B, Hogarth L, Tseng LJ, Teige JC, Shadel WG, DiBenedetti DB, Danto S, Lee TC, Price LH, Niaura R. Dissociable effect of acute varenicline on tonic versus cue-provoked craving in non-treatment-motivated heavy smokers. Drug Alcohol Depend. 2013 Jun 1;130(1-3):135-41. PubMed PMID: 23201174.

D. Hogarth L, Retzler C, Munafò MR, Tran DM, Troisi JR 2nd, Rose AK, Jones A, Field M. Extinction of cue-evoked drug-seeking relies on degrading hierarchical instrumental expectancies. Behav Res Ther. 2014 Aug;59:61-70. PMID: 25011113.

 

3. Habit learning theory of addiction in humans

My PhD supervisor, Anthony Dickinson, had previously developed the habit learning theory of addiction in animals, and this account has since become a popular account of addiction in humans. On this view, drug-seeking is at first goal-directed (driven by the expected value of the drug), and progressively becomes habitual through practice (automatically elicited by drug related contexts without forethought for the consequences). Individual differences in vulnerability to dependence is driven by a propensity for drug-seeking to shift from being goal-directed to habitual, making the behaviour less amenable to cognitive regulation. To test this prediction, I was the first person to develop an outcome devaluation protocol for humans with drug reinforcers based on the animal model (A,B) (top 5% and 6% cited respectively). This work revealed that although drug-seeking could be rendered habitual under conditions of acute alcohol intoxication(C) (top 9% cited) or cognitive load (D) (top 20% cited), under normal conditions, drug-seeking is goal-directed rather than habitual. Furthermore, more dependent individuals were not more susceptible to drug-seeking becoming habitual(A,B,C,D). Instead, they engage in higher frequency of goal-directed drug-seeking, suggesting dependence is driven by greater expected reward value of the drug (consistent with behavioural-economic accounts). I have concluded from these findings that the evidence for habitual drug-seeking in animals is a product of the invariant nature of their laboratory experience, and that habit theory does not account for addiction in human.

A. Hogarth L, Chase HW. Parallel goal-directed and habitual control of human drug-seeking: implications for dependence vulnerability. J Exp Psychol Anim Behav Process. 2011 Jul;37(3):261-76. PMID: 21500933.

B. Hogarth L. Goal-directed and transfer-cue-elicited drug-seeking are dissociated by pharmacotherapy: evidence for independent additive controllers. J Exp Psychol Anim Behav Process. 2012 Jul;38(3):266-78. PMID: 22823420.

C. Hogarth L, Attwood AS, Bate HA, Munafò MR. Acute alcohol impairs human goal-directed action. Biol Psychol. 2012 May;90(2):154-60. PMID: 22406757.

D. Hogarth L, Field M, Rose AK. Phasic transition from goal-directed to habitual control over drug-seeking produced by conflicting reinforcer expectancy. Addict Biol. 2013 Jan;18(1):88-97. PMID: 23167442.

 

4. Negative reinforcement theory of drug dependence

My previous work had suggested that individual differences in sub-clinical dependence is driven by the greater expected reward value of the drug driving higher rates of goal-directed drug-seeking. The suspicion, however, was that a second process contributed to clinical addiction. According to negative reinforcement theories, negative states such as depression, anxiety, withdrawal, cognitive deficits etc., powerfully motivate drug-seeking to acutely mitigate those states. Dr. Hitsman and myself hypothesized that individual sensitivity to such negative triggers motivating goal-directed drug-seeking would be the crucial process underpinning clinical dependence. In testing this hypothesis, we adapted the outcome-devaluation procedure to demonstrate that acute negative mood can powerfully motivate drug-seeking behavior, fully countermanding the capacity of drug satiety to reduce goal-directed drug-seeking(A). We then demonstrated that smokers with current major depression are more sensitive to negative mood and withdrawal induced motivation of tobacco-seeking(B) and young adult drinkers with depression symptoms are more sensitive to negative mood-induced increases in alcohol-seeking(C). We have also synthesized this goal-directed account of drug dependence vulnerability in a high profile review article(D). Overall, we argue that individual differences in sub-clinical dependence are driven by the greater expected reward value of the drug driving higher rates of goal-directed drug-seeking. This process is amplified by negative motivational states in groups with comorbid psychiatric symptoms, which powerfully promote goal-directed drug-seeking producing the pathological character of clinical addiction. Our current work focuses on hypersensitivity to negative triggers for drug use in groups with comorbid psychiatric illness, to inform understanding of mechanisms, as well as treatment and prevention strategies for vulnerable drug user groups.

A. Hogarth, L., He, Z., Chase, H. W., Wills, A. J., Troisi, J., II, Leventhal, A. M., (…), Hitsman, B. (2015). Negative mood reverses devaluation of goal-directed drug-seeking favouring an incentive learning account of drug dependence. Psychopharmacology, 232(17), 3235-3247.  PMID: 26041336.

B. Hogarth, L., Mathew, A. R., & Hitsman, B. (2017). Current major depression is associated with greater sensitivity to the motivational effect of both negative mood induction and abstinence on tobacco-seeking behavior. Drug and Alcohol Dependence, 176, 1-6. PMID: 28460322

C. Hogarth, L., Hardy, L., Mathew, A. R., & Hitsman, B. (in press) Negative mood-induced alcohol-seeking is greater in young adults who report depression symptoms, drinking to cope, and subjective reactivity. Experimental and Clinical Psychopharmacology.

D. Mathew, A. R., Hogarth, L., Leventhal, A. M., Cook, J. W., & Hitsman, B. (2017). Cigarette smoking and depression comorbidity: systematic review and proposed theoretical model. Addiction, 112(3), 401-412. PMID: 27628300.

 

Research projects

Grants/Funding:

2022 Medical Research Council. Reinforcer-specific value-based decision-making in persistence of and recovery from alcohol use disorder. Prof. Field, Sheffield (PI), Hogarth (CoI).

2020 South African Medical Research Council. Coping motives as a mediator of the relationship between trauma exposure and substance misuse in South African adolescents. Dr. Kaminer University of Cape Town (PI), Hogarth (CoI).

2019 ESRC postdoctoral fellowship to Lorna Hardy. Developing a coping motives targeted brief intervention for high-risk young drinkers. Hogarth (CoI).

2018 MRC Confidence in Global Mental Health pump priming award. South African adolescents’ vulnerability to drug dependence. Hogarth (PI) and Prof Seedat, Stellenbosch University (PI).

2017 Alcohol Research Council grant: The therapeutic effect of Brief Adaptive Coping Training (BACT) on relapse to alcohol provoked by negative emotional experience.Hogarth (PI).

2013 Australian Research Council Grant: Advancing the science of willpower - investigating the mechanisms and processes of self-control. Prof. Hagger, Curtin University (PI) 

2012 ESRC Project Grant: Alcohol seeking and consumption - the role of reward valuation and attentional bias. Dr. Rose, University of Liverpool (PI) Hogarth (CoI).

2011 MRC Project Grant: Human drug dependence - cognitive predisposition and neural mechanisms. Hogarth (PI).

2011 Alcohol Education and Research council grant: Neurophysiological correlates of Pavlovian to instrumental transfer in heavy drinkers. Dr. Matt Field, University of Liverpool (PI), Hogarth (CoI).

2007 BBSRC Project Grant: Attentional mediation of conditioned appetitive behaviour in humans. With Prof. Duka, University of Sussex (PI), Prof. Dickinson, University of Cambridge (PI), Hogarth (CoI).

Research networks

See recent publication co-authors.

Publications

Key publications | Publications by category | Publications by year

Key publications


Hogarth L, Mathew AR, Hitsman B (In Press). Current major depression is associated with greater sensitivity to the motivational effect of both negative mood induction and abstinence on tobacco-seeking behavior. Drug and Alcohol Dependence
Hogarth L, Lam-Cassettari C, Pacitti H, Currah T, Mahlberg J, Hartley L, Moustafa A (2018). Intact goal-directed control in treatment-seeking drug users indexed by outcome-devaluation and Pavlovian to instrumental transfer: Critique of habit theory. European Journal of Neuroscience, 50(3), 2513-2525.
Mathew AR, Hogarth L, Leventhal AM, Cook JW, Hitsman B (2017). Cigarette smoking and depression comorbidity: systematic review and proposed theoretical model. Addiction, 112(3), 401-412. Abstract.  Author URL.
Hogarth L, He Z, Chase HW, Wills AJ, Troisi J, Leventhal AM, Mathew AR, Hitsman B (2015). Negative mood reverses devaluation of goal-directed drug-seeking favouring an incentive learning account of drug dependence. Psychopharmacology (Berl), 232(17), 3235-3247. Abstract.  Author URL.
Hogarth L, Maynard OM, Munafò MR (2015). Plain cigarette packs do not exert Pavlovian to instrumental transfer of control over tobacco-seeking. Addiction, 110(1), 174-182. Abstract.  Author URL.
Hogarth L, Retzler C, Munafò MR, Tran DMD, Troisi JR, Rose AK, Jones A, Field M (2014). Extinction of cue-evoked drug-seeking relies on degrading hierarchical instrumental expectancies. Behav Res Ther, 59, 61-70. Abstract.  Author URL.

Publications by category


Books

Hogarth L (2018). A Critical Review of Habit Theory of Drug Dependence.
Hogarth L (2018). Controlled and automatic learning processes in addiction.
Haselgrove M, Hogarth L (2011). Clinical Applications of Learning Theory., Psychology Press. Abstract.

Journal articles

Hardy L, Hogarth L (In Press). A novel concurrent pictorial choice model of mood-induced relapse in hazardous drinkers. Experimental and clinical psychopharmacology
Hogarth L (In Press). Addiction is driven by excessive goal-directed drug choice under negative affect: Translational critique of habit and compulsion theory. Neuropsychopharmacology
Rose AK, Brown K, MacKillop J, Field M, Hogarth L (In Press). Alcohol devaluation has dissociable effects on distinct components of alcohol behaviour. Psychopharmacology
Hogarth L, Mathew AR, Hitsman B (In Press). Current major depression is associated with greater sensitivity to the motivational effect of both negative mood induction and abstinence on tobacco-seeking behavior. Drug and Alcohol Dependence
Hogarth L, Seabrooke T, Edmunds C, Mitchell C (In Press). Goal-directed control in Pavlovian-instrumental transfer. Journal of Experimental Psychology: Animal Learning and Cognition
Hogarth L (In Press). State Anxiety and Alcohol Choice: Evidence from Experimental and Online Observational Studies. Journal of Psychopharmacology
Hogarth L, Shuai R, Bakou AE, Hardy L (In Press). Ultra-brief breath counting (mindfulness) training promotes recovery from stress-induced alcohol-seeking in student drinkers. Addictive Behaviors
Herchenroeder L, Williams E, Wedell E, Sorid SD, Bakou AE, Bravo AJ, Hogarth L (2022). Interoceptive attention or merely distraction? an examination of the effects of brief breath counting training on stress-induced alcohol-seeking behavior. Experimental and Clinical Psychopharmacology
Shuai R, Anker JJ, Bravo AJ, Kushner MG, Hogarth L (2022). Risk Pathways Contributing to the Alcohol Harm Paradox: Socioeconomic Deprivation Confers Susceptibility to Alcohol Dependence via Greater Exposure to Aversive Experience, Internalizing Symptoms and Drinking to Cope. Frontiers in Behavioral Neuroscience, 16 Abstract.
Smith NIJ, Gilmour S, Prescott-Mayling L, Hogarth L, Corrigan JD, Williams WH (2021). A pilot study of brain injury in police officers: a source of mental health problems?. J Psychiatr Ment Health Nurs, 28(1), 43-55. Abstract.  Author URL.
Hardy L, Bakou AE, Shuai R, Acuff SF, MacKillop J, Murphy CM, Murphy JG, Hogarth L (2021). Associations between the Brief Assessment of Alcohol Demand (BAAD) questionnaire and alcohol use disorder severity in UK samples of student and community drinkers. Addictive Behaviors, 113, 106724-106724.
Bakou AE, Shuai R, Hogarth L (2021). Brief Negative Affect Focused Functional Imagery Training Abolishes Stress-Induced Alcohol Choice in Hazardous Student Drinkers. Journal of Addiction, 2021, 1-7. Abstract.
Shuai R, Bakou AE, Andrade J, Hides L, Hogarth L (2021). Brief Online Negative Affect Focused Functional Imagery Training Improves 2-Week Drinking Outcomes in Hazardous Student Drinkers: a Pilot Randomised Controlled Trial. International Journal of Behavioral Medicine, 29(3), 346-356. Abstract.
Mahlberg J, Seabrooke T, Weidemann G, Hogarth L, Mitchell CJ, Moustafa AA (2021). Human appetitive Pavlovian-to-instrumental transfer: a goal-directed account. PSYCHOLOGICAL RESEARCH-PSYCHOLOGISCHE FORSCHUNG, 85(2), 449-463. Author URL.
Kent H, Williams WH, Hogarth L, Mewse A, Kent H (2021). Poor Parental Supervision is Associated with Traumatic Brain Injury and Reactive Aggression in Young Offenders. Journal of Head Trauma Rehabilitation Abstract.
Acuff SF, Pilatti A, Collins M, Hides L, Thingujam NS, Chai WJ, Yap WM, Shuai R, Hogarth L, Bravo AJ, et al (2021). Reinforcer pathology of internet-related behaviors among college students: Data from six countries. Exp Clin Psychopharmacol Abstract.  Author URL.
Rycroft N, Hogarth L, MacKillop J, Dawkins L (2021). Vapers exhibit similar subjective nicotine dependence but lower nicotine reinforcing value compared to smokers. Addict Behav, 115 Abstract.  Author URL.
Bravo AJ, Prince MA, Pilatti A, Mezquita L, Keough MT, Hogarth L (2021). Young adult concurrent use and simultaneous use of alcohol and marijuana: a cross-national examination among college students in seven countries. Addictive Behaviors Reports, 14, 100373-100373.
Hogarth L, Field M (2020). Relative expected value of drugs versus competing rewards underpins vulnerability to and recovery from addiction. Behav Brain Res, 394 Abstract.  Author URL.
Seabrooke T, Wills AJ, Hogarth L, Mitchell CJ (2019). Automaticity and cognitive control: Effects of cognitive load on cue-controlled reward choice. Quarterly journal of experimental psychology (2006), 72(6), 1507-1521. Abstract.
Hogarth L (2019). Cue-elicited craving and human Pavlovian-to-instrumental transfer. Addiction Research & Theory
Hogarth L, Hardy L, Bakou A, Mahlberg J, Weidemann G, Cashel S, Moustafa AA (2019). Negative Mood Induction Increases Choice of Heroin Versus Food Pictures in Opiate-Dependent Individuals: Correlation with Self-Medication Coping Motives and Subjective Reactivity. FRONTIERS IN PSYCHIATRY, 10 Author URL.
Hogarth L (2019). Relationship between childhood abuse and substance misuse problems is mediated by substance use coping motives, in school attending South African adolescents. Drug and Alcohol Dependence
Hogarth L (2018). A concurrent pictorial drug choice task marks multiple risk factors in treatment-engaged smokers and drinkers. Behavioural Pharmacology
Hogarth L (2018). Alcohol use disorder symptoms are associated with greater relative value ascribed to alcohol, but not greater discounting of costs imposed on alcohol. Psychopharmacology
Miele A, Thompson M, Jao NC, Kalhan R, Leone F, Hogarth L, Hitsman B, Schnoll R (2018). Cancer Patients Enrolled in a Smoking Cessation Clinical Trial: Characteristics and Correlates of Smoking Rate and Nicotine Dependence. Journal of addiction
Hardy L, Josephy K, McAndrew A, Hawksley P, Hartley L, Hogarth L (2018). Evaluation of the Peninsula Alcohol and Violence Programme (PAVP) with violent offenders. Addiction Research & Theory, 0, 1-8. Abstract.
Hogarth L, Lam-Cassettari C, Pacitti H, Currah T, Mahlberg J, Hartley L, Moustafa A (2018). Intact goal-directed control in treatment-seeking drug users indexed by outcome-devaluation and Pavlovian to instrumental transfer: Critique of habit theory. European Journal of Neuroscience, 50(3), 2513-2525.
Pritchard TL, Weidemann G, Hogarth L (2018). Negative emotional appraisal selectively disrupts retrieval of expected outcome values required for goal-directed instrumental choice. Cogn Emot, 32(4), 843-851. Abstract.  Author URL.
Hogarth L (2018). Negative mood-induced alcohol-seeking is greater in young adults who report depression symptoms, drinking to cope, and subjective reactivity. Experimental and Clinical Psychopharmacology
Mathew AR, Hogarth L, Leventhal AM, Cook JW, Hitsman B (2017). Cigarette smoking and depression comorbidity: systematic review and proposed theoretical model. Addiction, 112(3), 401-412. Abstract.  Author URL.
Hogarth L, Hardy L (2017). Depressive statements prime goal-directed alcohol-seeking in individuals who report drinking to cope with negative affect. Psychopharmacology, 235, 269-279.
Hardy L, Mitchell C, Seabrooke T, Hogarth L (2017). Drug cue reactivity involves hierarchical instrumental learning: evidence from a biconditional Pavlovian to instrumental transfer task. Psychopharmacology (Berl), 234(13), 1977-1984. Abstract.  Author URL.
Seabrooke T, Le Pelley ME, Hogarth L, Mitchell CJ (2017). Evidence of a goal-directed process in human Pavlovian-instrumental transfer. J Exp Psychol Anim Learn Cogn, 43(4), 377-387. Abstract.  Author URL.
Myers CE, Rego J, Haber P, Morley K, Beck KD, Hogarth L, Moustafa AA (2017). Learning and generalization from reward and punishment in opioid addiction. Behav Brain Res, 317, 122-131. Abstract.  Author URL.
Mahlberg J, Haber P, Morley K, Weidemann G, Hogarth L, Beck KD, Myers CE, Moustafa AA (2017). Reward and punishment-based compound cue learning and generalization in opiate dependency. Exp Brain Res, 235(10), 3153-3162. Abstract.  Author URL.
Mathew AR, Hogarth L, Leventhal AM, Cook JW, Hitsman B (2016). Cigarette smoking and depression comorbidity: systematic review & proposed theoretical model. Addiction
Sheynin J, Moustafa AA, Beck KD, Servatius RJ, Casbolt PA, Haber P, Elsayed M, Hogarth L, Myers CE (2016). Exaggerated acquisition and resistance to extinction of avoidance behavior in treated heroin-dependent men. J Clin Psychiatry, 77(3), 386-394. Abstract.  Author URL.
Myers CE, Sheynin J, Balsdon T, Luzardo A, Beck KD, Hogarth L, Haber P, Moustafa AA (2016). Probabilistic reward- and punishment-based learning in opioid addiction: Experimental and computational data. Behav Brain Res, 296, 240-248. Abstract.  Author URL.
Seabrooke T, Hogarth L, Mitchell CJ (2016). The propositional basis of cue-controlled reward seeking. Q J Exp Psychol (Hove), 69(12), 2452-2470. Abstract.  Author URL.
Field M, Werthmann J, Franken I, Hofmann W, Hogarth L, Roefs A (2016). The role of attentional bias in obesity and addiction. Health Psychol, 35(8), 767-780. Abstract.  Author URL.
Panlilio LV, Hogarth L, Shoaib M (2015). Concurrent access to nicotine and sucrose in rats. Psychopharmacology (Berl), 232(8), 1451-1460. Abstract.  Author URL.
Maynard OM, Leonards U, Attwood AS, Bauld L, Hogarth L, Munafò MR (2015). Effects of first exposure to plain cigarette packaging on smoking behaviour and attitudes: a randomised controlled study. BMC Public Health, 15(1). Abstract.
Hogarth L, He Z, Chase HW, Wills AJ, Troisi J, Leventhal AM, Mathew AR, Hitsman B (2015). Negative mood reverses devaluation of goal-directed drug-seeking favouring an incentive learning account of drug dependence. Psychopharmacology (Berl), 232(17), 3235-3247. Abstract.  Author URL.
Hogarth L, Maynard OM, Munafò MR (2015). Plain cigarette packs do not exert Pavlovian to instrumental transfer of control over tobacco-seeking. Addiction, 110(1), 174-182. Abstract.  Author URL.
Martinovic J, Jones A, Christiansen P, Rose AK, Hogarth L, Field M (2014). Electrophysiological responses to alcohol cues are not associated with Pavlovian-to-instrumental transfer in social drinkers. PLoS One, 9(4). Abstract.  Author URL.
Hogarth L, Retzler C, Munafò MR, Tran DMD, Troisi JR, Rose AK, Jones A, Field M (2014). Extinction of cue-evoked drug-seeking relies on degrading hierarchical instrumental expectancies. Behav Res Ther, 59, 61-70. Abstract.  Author URL.
Maynard OM, Leonards U, Attwood AS, Bauld L, Hogarth L, Munafò MR (2014). Plain packaging of cigarettes and smoking behavior: study protocol for a randomized controlled study. Trials, 15 Abstract.  Author URL.
Hogarth L, Balleine BW, Corbit LH, Killcross S (2013). Associative learning mechanisms underpinning the transition from recreational drug use to addiction. Ann N Y Acad Sci, 1282, 12-24. Abstract.  Author URL.
Hogarth L, Stillwell DJ, Tunney RJ (2013). BIS impulsivity and acute nicotine exposure are associated with discounting global consequences in the Harvard game. Hum Psychopharmacol, 28(1), 72-79. Abstract.  Author URL.
Hitsman B, Hogarth L, Tseng L-J, Teige JC, Shadel WG, DiBenedetti DB, Danto S, Lee TC, Price LH, Niaura R, et al (2013). Dissociable effect of acute varenicline on tonic versus cue-provoked craving in non-treatment-motivated heavy smokers. Drug and Alcohol Dependence, 130, 135-141.
Chase HW, Mackillop J, Hogarth L (2013). Isolating behavioural economic indices of demand in relation to nicotine dependence. Psychopharmacology (Berl), 226(2), 371-380. Abstract.  Author URL.
Hogarth L, Field M, Rose AK (2013). Phasic transition from goal-directed to habitual control over drug-seeking produced by conflicting reinforcer expectancy. Addiction Biology, 18, 88-97.
Rose AK, Brown K, Field M, Hogarth L (2013). The contributions of value-based decision-making and attentional bias to alcohol-seeking following devaluation. Addiction, 108(7), 1241-1249. Abstract.  Author URL.
Hogarth L, Attwood AS, Bate HA, Munafò MR (2012). Acute alcohol impairs human goal-directed action. Biol Psychol, 90(2), 154-160. Abstract.  Author URL.
Hogarth L, Chase HW (2012). Evaluating psychological markers for human nicotine dependence: tobacco choice, extinction, and Pavlovian-to-instrumental transfer. Exp Clin Psychopharmacol, 20(3), 213-224. Abstract.  Author URL.
Hogarth L (2012). Goal-directed and transfer-cue-elicited drug-seeking are dissociated by pharmacotherapy: evidence for independent additive controllers. J Exp Psychol Anim Behav Process, 38(3), 266-278. Abstract.  Author URL.
Hogarth L, Chase HW, Baess K (2012). Impaired goal-directed behavioural control in human impulsivity. Q J Exp Psychol (Hove), 65(2), 305-316. Abstract.  Author URL.
Jones A, Hogarth L, Christiansen P, Rose AK, Martinovic J, Field M (2012). Reward expectancy promotes generalized increases in attentional bias for rewarding stimuli. Q J Exp Psychol (Hove), 65(12), 2333-2342. Abstract.  Author URL.
Field M, Hogarth L, Bleasdale D, Wright P, Fernie G, Christiansen P (2011). Alcohol expectancy moderates attentional bias for alcohol cues in light drinkers. Addiction, 106(6), 1097-1103. Abstract.  Author URL.
Craig M, Pennacchia A, Wright NR, Chase HW, Hogarth L (2011). Evaluation of un-medicated, self-paced alcohol withdrawal. PLoS One, 6(7). Abstract.  Author URL.
Chase HW, Hogarth L (2011). Impulsivity and symptoms of nicotine dependence in a young adult population. Nicotine Tob Res, 13(12), 1321-1325. Abstract.  Author URL.
Hogarth L, Chase HW (2011). Parallel goal-directed and habitual control of human drug-seeking: implications for dependence vulnerability. J Exp Psychol Anim Behav Process, 37(3), 261-276. Abstract.  Author URL.
Trick L, Hogarth L, Duka T (2011). Prediction and uncertainty in human Pavlovian to instrumental transfer. J Exp Psychol Learn Mem Cogn, 37(3), 757-765. Abstract.  Author URL.
Chase HW, Eickhoff SB, Laird AR, Hogarth L (2011). The neural basis of drug stimulus processing and craving: an activation likelihood estimation meta-analysis. Biol Psychiatry, 70(8), 785-793. Abstract.  Author URL.
Hogarth L (2011). The role of impulsivity in the aetiology of drug dependence: reward sensitivity versus automaticity. Psychopharmacology (Berl), 215(3), 567-580. Abstract.  Author URL.
Hogarth L, Dickinson A, Duka T (2010). The associative basis of cue-elicited drug taking in humans. Psychopharmacology (Berl), 208(3), 337-351. Abstract.  Author URL.
Hogarth L, Dickinson A, Duka T (2009). Detection versus sustained attention to drug cues have dissociable roles in mediating drug seeking behavior. Exp Clin Psychopharmacol, 17(1), 21-30. Abstract.  Author URL.
Hogarth L, Dickinson A, Austin A, Brown C, Duka T (2008). Attention and expectation in human predictive learning: the role of uncertainty. Q J Exp Psychol (Hove), 61(11), 1658-1668. Abstract.  Author URL.
Hogarth L, Dickinson A, Janowski M, Nikitina A, Duka T (2008). The role of attentional bias in mediating human drug-seeking behaviour. Psychopharmacology (Berl), 201(1), 29-41. Abstract.  Author URL.
Hogarth L, Dickinson A, Wright A, Kouvaraki M, Duka T (2007). The role of drug expectancy in the control of human drug seeking. J Exp Psychol Anim Behav Process, 33(4), 484-496. Abstract.  Author URL.
Hogarth L, Dickinson A, Hutton SB, Bamborough H, Duka T (2006). Contingency knowledge is necessary for learned motivated behaviour in humans: relevance for addictive behaviour. Addiction, 101(8), 1153-1166. Abstract.  Author URL.
Hogarth L, Dickinson A, Hutton SB, Elbers N, Duka T (2006). Drug expectancy is necessary for stimulus control of human attention, instrumental drug-seeking behaviour and subjective pleasure. Psychopharmacology (Berl), 185(4), 495-504. Abstract.  Author URL.
Hogarth L, Duka T (2006). Human nicotine conditioning requires explicit contingency knowledge: is addictive behaviour cognitively mediated?. Psychopharmacology (Berl), 184(3-4), 553-566. Abstract.  Author URL.
Hogarth L, Dickinson A, Duka T (2005). Explicit knowledge of stimulus-outcome contingencies and stimulus control of selective attention and instrumental action in human smoking behaviour. Psychopharmacology (Berl), 177(4), 428-437. Abstract.  Author URL.
Stephens DN, Ripley TL, Borlikova G, Schubert M, Albrecht D, Hogarth L, Duka T (2005). Repeated ethanol exposure and withdrawal impairs human fear conditioning and depresses long-term potentiation in rat amygdala and hippocampus. Biol Psychiatry, 58(5), 392-400. Abstract.  Author URL.
Hogarth LC, Mogg K, Bradley BP, Duka T, Dickinson A (2003). Attentional orienting towards smoking-related stimuli. Behavioural Pharmacology, 14, 153-160.
Hogarth LC, Mogg K, Bradley BP, Duka T, Dickinson A (2003). Attentional orienting towards smoking-related stimuli. Behavioural Pharmacology, 14(2), 153-160. Abstract.
Hogarth L, Dickinson A, Duka T (2003). Discriminative stimuli that control instrumental tobacco-seeking by human smokers also command selective attention. Psychopharmacology (Berl), 168(4), 435-445. Abstract.  Author URL.

Chapters

Hogarth L, Troisi JR (2015). A hierarchical instrumental decision theory of nicotine dependence. In  (Ed) , 165-191.  Abstract.  Author URL.
Hogarth L, Chase HW (2013). Vulnerabilities underlying human drug dependence: Goal valuation versus habit learning. In  (Ed) , 75-101.
Hogarth L, Dickinson A, Duka T (2010). Selective attention to conditioned stimuli in human discrimination learning: Untangling the effect of outcome prediction, valence, arousal and uncertainty. In Mitchell CJ, Pelley MEL (Eds.) Attention and Associative Learning, Oxford University Press, 71-98.  Abstract.

Conferences

Rose AK, Hogarth L, Brown K (2012). ATTENTIONAL PROCESSES AND THE ABILITY OF ALCOHOL CUES TO TRIGGER HABIT-LIKE ALCOHOL-SEEKING BEHAVIOUR.  Author URL.
Hogarth L, Rose AK (2012). GOAL-DIRECTED CONTROL OVER ACTION SELECTION IN HUMANS IS IMPAIRED BY ACUTE ALCOHOL ADMINISTRATION AND ALCOHOL CUES.  Author URL.
Rose AK, Hogarth L, Brown K (2012). THE ROLE OF ATTENTION IN MEDIATING GOAL-DIRECTED ALCOHOL SEEKING.  Author URL.
Norman NA, Hogarth L, Panlilio L, Shoaib M (2011). ESTABLISHING CONCURRENT CHOICE PROCEDURES WITH INTRAVENOUS NICOTINE AND SUCROSE IN RATS.  Author URL.
Norman N, Hogarth L, Panlilio L, Shoaib M (2011). ESTABLISHING CONCURRENT CHOICE PROCEDURES WITH INTRAVENOUS NICOTINE AND SUCROSE IN RATS.  Author URL.
Esfandiari A, Shoaib M, Hogarth L, Panlilio L (2011). ESTABLISHING PAVLOVIAN TO INSTRUMENTAL TRANSFER (PIT) WITH INTRAVENOUS NICOTINE AND SUCROSE IN RATS.  Author URL.
Rose AK, Hogarth L (2011). THE ROLE OF CHOICE IN ALCOHOL DEPENDENCE.  Author URL.
Duka T, Townshend J, Hogarth L, Stephens D (2007). Impaired learning of conditioned fear in alcoholics with a history of multiple detoxifications and in binge drinkers.  Author URL.
Hogarth L, Dickinson A, Wright A, Kouvaraki M, Duka T (2007). The role of drug expectancy in the control of human drug seeking.  Author URL.
Hogarth L, Dickinson A, Hutton SB, Bamborough H, Duka T (2005). Stimulus control of human selective attention and instrumental avoidance behaviour depends upon explicit contingency knowledge.  Author URL.
Hogarth L, Dickinson A, Hutton SB, Duka T (2005). The control of human selective attention by cues associated with nicotine.  Author URL.

Publications by year


In Press

Hardy L, Hogarth L (In Press). A novel concurrent pictorial choice model of mood-induced relapse in hazardous drinkers. Experimental and clinical psychopharmacology
Hogarth L (In Press). Addiction is driven by excessive goal-directed drug choice under negative affect: Translational critique of habit and compulsion theory. Neuropsychopharmacology
Rose AK, Brown K, MacKillop J, Field M, Hogarth L (In Press). Alcohol devaluation has dissociable effects on distinct components of alcohol behaviour. Psychopharmacology
Hogarth L, Mathew AR, Hitsman B (In Press). Current major depression is associated with greater sensitivity to the motivational effect of both negative mood induction and abstinence on tobacco-seeking behavior. Drug and Alcohol Dependence
Hogarth L, Seabrooke T, Edmunds C, Mitchell C (In Press). Goal-directed control in Pavlovian-instrumental transfer. Journal of Experimental Psychology: Animal Learning and Cognition
Hogarth L (In Press). State Anxiety and Alcohol Choice: Evidence from Experimental and Online Observational Studies. Journal of Psychopharmacology
Hogarth L, Shuai R, Bakou AE, Hardy L (In Press). Ultra-brief breath counting (mindfulness) training promotes recovery from stress-induced alcohol-seeking in student drinkers. Addictive Behaviors

2022

Herchenroeder L, Williams E, Wedell E, Sorid SD, Bakou AE, Bravo AJ, Hogarth L (2022). Interoceptive attention or merely distraction? an examination of the effects of brief breath counting training on stress-induced alcohol-seeking behavior. Experimental and Clinical Psychopharmacology
Shuai R, Anker JJ, Bravo AJ, Kushner MG, Hogarth L (2022). Risk Pathways Contributing to the Alcohol Harm Paradox: Socioeconomic Deprivation Confers Susceptibility to Alcohol Dependence via Greater Exposure to Aversive Experience, Internalizing Symptoms and Drinking to Cope. Frontiers in Behavioral Neuroscience, 16 Abstract.

2021

Smith NIJ, Gilmour S, Prescott-Mayling L, Hogarth L, Corrigan JD, Williams WH (2021). A pilot study of brain injury in police officers: a source of mental health problems?. J Psychiatr Ment Health Nurs, 28(1), 43-55. Abstract.  Author URL.
Hardy L, Bakou AE, Shuai R, Acuff SF, MacKillop J, Murphy CM, Murphy JG, Hogarth L (2021). Associations between the Brief Assessment of Alcohol Demand (BAAD) questionnaire and alcohol use disorder severity in UK samples of student and community drinkers. Addictive Behaviors, 113, 106724-106724.
Bakou AE, Shuai R, Hogarth L (2021). Brief Negative Affect Focused Functional Imagery Training Abolishes Stress-Induced Alcohol Choice in Hazardous Student Drinkers. Journal of Addiction, 2021, 1-7. Abstract.
Shuai R, Bakou AE, Andrade J, Hides L, Hogarth L (2021). Brief Online Negative Affect Focused Functional Imagery Training Improves 2-Week Drinking Outcomes in Hazardous Student Drinkers: a Pilot Randomised Controlled Trial. International Journal of Behavioral Medicine, 29(3), 346-356. Abstract.
Mahlberg J, Seabrooke T, Weidemann G, Hogarth L, Mitchell CJ, Moustafa AA (2021). Human appetitive Pavlovian-to-instrumental transfer: a goal-directed account. PSYCHOLOGICAL RESEARCH-PSYCHOLOGISCHE FORSCHUNG, 85(2), 449-463. Author URL.
Kent H, Williams WH, Hogarth L, Mewse A, Kent H (2021). Poor Parental Supervision is Associated with Traumatic Brain Injury and Reactive Aggression in Young Offenders. Journal of Head Trauma Rehabilitation Abstract.
Acuff SF, Pilatti A, Collins M, Hides L, Thingujam NS, Chai WJ, Yap WM, Shuai R, Hogarth L, Bravo AJ, et al (2021). Reinforcer pathology of internet-related behaviors among college students: Data from six countries. Exp Clin Psychopharmacol Abstract.  Author URL.
Rycroft N, Hogarth L, MacKillop J, Dawkins L (2021). Vapers exhibit similar subjective nicotine dependence but lower nicotine reinforcing value compared to smokers. Addict Behav, 115 Abstract.  Author URL.
Bravo AJ, Prince MA, Pilatti A, Mezquita L, Keough MT, Hogarth L (2021). Young adult concurrent use and simultaneous use of alcohol and marijuana: a cross-national examination among college students in seven countries. Addictive Behaviors Reports, 14, 100373-100373.

2020

Hogarth L, Field M (2020). Relative expected value of drugs versus competing rewards underpins vulnerability to and recovery from addiction. Behav Brain Res, 394 Abstract.  Author URL.

2019

Seabrooke T, Wills AJ, Hogarth L, Mitchell CJ (2019). Automaticity and cognitive control: Effects of cognitive load on cue-controlled reward choice. Quarterly journal of experimental psychology (2006), 72(6), 1507-1521. Abstract.
Hogarth L (2019). Cue-elicited craving and human Pavlovian-to-instrumental transfer. Addiction Research & Theory
Hogarth L, Hardy L, Bakou A, Mahlberg J, Weidemann G, Cashel S, Moustafa AA (2019). Negative Mood Induction Increases Choice of Heroin Versus Food Pictures in Opiate-Dependent Individuals: Correlation with Self-Medication Coping Motives and Subjective Reactivity. FRONTIERS IN PSYCHIATRY, 10 Author URL.
Hogarth L (2019). Relationship between childhood abuse and substance misuse problems is mediated by substance use coping motives, in school attending South African adolescents. Drug and Alcohol Dependence

2018

Hogarth L (2018). A Critical Review of Habit Theory of Drug Dependence.
Hogarth L (2018). A concurrent pictorial drug choice task marks multiple risk factors in treatment-engaged smokers and drinkers. Behavioural Pharmacology
Hogarth L (2018). Alcohol use disorder symptoms are associated with greater relative value ascribed to alcohol, but not greater discounting of costs imposed on alcohol. Psychopharmacology
Miele A, Thompson M, Jao NC, Kalhan R, Leone F, Hogarth L, Hitsman B, Schnoll R (2018). Cancer Patients Enrolled in a Smoking Cessation Clinical Trial: Characteristics and Correlates of Smoking Rate and Nicotine Dependence. Journal of addiction
Hogarth L (2018). Controlled and automatic learning processes in addiction.
Hardy L, Josephy K, McAndrew A, Hawksley P, Hartley L, Hogarth L (2018). Evaluation of the Peninsula Alcohol and Violence Programme (PAVP) with violent offenders. Addiction Research & Theory, 0, 1-8. Abstract.
Hogarth L, Lam-Cassettari C, Pacitti H, Currah T, Mahlberg J, Hartley L, Moustafa A (2018). Intact goal-directed control in treatment-seeking drug users indexed by outcome-devaluation and Pavlovian to instrumental transfer: Critique of habit theory. European Journal of Neuroscience, 50(3), 2513-2525.
Pritchard TL, Weidemann G, Hogarth L (2018). Negative emotional appraisal selectively disrupts retrieval of expected outcome values required for goal-directed instrumental choice. Cogn Emot, 32(4), 843-851. Abstract.  Author URL.
Hogarth L (2018). Negative mood-induced alcohol-seeking is greater in young adults who report depression symptoms, drinking to cope, and subjective reactivity. Experimental and Clinical Psychopharmacology

2017

Mathew AR, Hogarth L, Leventhal AM, Cook JW, Hitsman B (2017). Cigarette smoking and depression comorbidity: systematic review and proposed theoretical model. Addiction, 112(3), 401-412. Abstract.  Author URL.
Hogarth L, Hardy L (2017). Depressive statements prime goal-directed alcohol-seeking in individuals who report drinking to cope with negative affect. Psychopharmacology, 235, 269-279.
Hardy L, Mitchell C, Seabrooke T, Hogarth L (2017). Drug cue reactivity involves hierarchical instrumental learning: evidence from a biconditional Pavlovian to instrumental transfer task. Psychopharmacology (Berl), 234(13), 1977-1984. Abstract.  Author URL.
Seabrooke T, Le Pelley ME, Hogarth L, Mitchell CJ (2017). Evidence of a goal-directed process in human Pavlovian-instrumental transfer. J Exp Psychol Anim Learn Cogn, 43(4), 377-387. Abstract.  Author URL.
Myers CE, Rego J, Haber P, Morley K, Beck KD, Hogarth L, Moustafa AA (2017). Learning and generalization from reward and punishment in opioid addiction. Behav Brain Res, 317, 122-131. Abstract.  Author URL.
Mahlberg J, Haber P, Morley K, Weidemann G, Hogarth L, Beck KD, Myers CE, Moustafa AA (2017). Reward and punishment-based compound cue learning and generalization in opiate dependency. Exp Brain Res, 235(10), 3153-3162. Abstract.  Author URL.

2016

Mathew AR, Hogarth L, Leventhal AM, Cook JW, Hitsman B (2016). Cigarette smoking and depression comorbidity: systematic review & proposed theoretical model. Addiction
Sheynin J, Moustafa AA, Beck KD, Servatius RJ, Casbolt PA, Haber P, Elsayed M, Hogarth L, Myers CE (2016). Exaggerated acquisition and resistance to extinction of avoidance behavior in treated heroin-dependent men. J Clin Psychiatry, 77(3), 386-394. Abstract.  Author URL.
Myers CE, Sheynin J, Balsdon T, Luzardo A, Beck KD, Hogarth L, Haber P, Moustafa AA (2016). Probabilistic reward- and punishment-based learning in opioid addiction: Experimental and computational data. Behav Brain Res, 296, 240-248. Abstract.  Author URL.
Seabrooke T, Hogarth L, Mitchell CJ (2016). The propositional basis of cue-controlled reward seeking. Q J Exp Psychol (Hove), 69(12), 2452-2470. Abstract.  Author URL.
Field M, Werthmann J, Franken I, Hofmann W, Hogarth L, Roefs A (2016). The role of attentional bias in obesity and addiction. Health Psychol, 35(8), 767-780. Abstract.  Author URL.

2015

Hogarth L, Troisi JR (2015). A hierarchical instrumental decision theory of nicotine dependence. In  (Ed) , 165-191.  Abstract.  Author URL.
Panlilio LV, Hogarth L, Shoaib M (2015). Concurrent access to nicotine and sucrose in rats. Psychopharmacology (Berl), 232(8), 1451-1460. Abstract.  Author URL.
Maynard OM, Leonards U, Attwood AS, Bauld L, Hogarth L, Munafò MR (2015). Effects of first exposure to plain cigarette packaging on smoking behaviour and attitudes: a randomised controlled study. BMC Public Health, 15(1). Abstract.
Hogarth L, He Z, Chase HW, Wills AJ, Troisi J, Leventhal AM, Mathew AR, Hitsman B (2015). Negative mood reverses devaluation of goal-directed drug-seeking favouring an incentive learning account of drug dependence. Psychopharmacology (Berl), 232(17), 3235-3247. Abstract.  Author URL.
Hogarth L, Maynard OM, Munafò MR (2015). Plain cigarette packs do not exert Pavlovian to instrumental transfer of control over tobacco-seeking. Addiction, 110(1), 174-182. Abstract.  Author URL.

2014

Martinovic J, Jones A, Christiansen P, Rose AK, Hogarth L, Field M (2014). Electrophysiological responses to alcohol cues are not associated with Pavlovian-to-instrumental transfer in social drinkers. PLoS One, 9(4). Abstract.  Author URL.
Hogarth L, Retzler C, Munafò MR, Tran DMD, Troisi JR, Rose AK, Jones A, Field M (2014). Extinction of cue-evoked drug-seeking relies on degrading hierarchical instrumental expectancies. Behav Res Ther, 59, 61-70. Abstract.  Author URL.
Maynard OM, Leonards U, Attwood AS, Bauld L, Hogarth L, Munafò MR (2014). Plain packaging of cigarettes and smoking behavior: study protocol for a randomized controlled study. Trials, 15 Abstract.  Author URL.

2013

Hogarth L, Balleine BW, Corbit LH, Killcross S (2013). Associative learning mechanisms underpinning the transition from recreational drug use to addiction. Ann N Y Acad Sci, 1282, 12-24. Abstract.  Author URL.
Hogarth L, Stillwell DJ, Tunney RJ (2013). BIS impulsivity and acute nicotine exposure are associated with discounting global consequences in the Harvard game. Hum Psychopharmacol, 28(1), 72-79. Abstract.  Author URL.
Hitsman B, Hogarth L, Tseng L-J, Teige JC, Shadel WG, DiBenedetti DB, Danto S, Lee TC, Price LH, Niaura R, et al (2013). Dissociable effect of acute varenicline on tonic versus cue-provoked craving in non-treatment-motivated heavy smokers. Drug and Alcohol Dependence, 130, 135-141.
Chase HW, Mackillop J, Hogarth L (2013). Isolating behavioural economic indices of demand in relation to nicotine dependence. Psychopharmacology (Berl), 226(2), 371-380. Abstract.  Author URL.
Hogarth L, Field M, Rose AK (2013). Phasic transition from goal-directed to habitual control over drug-seeking produced by conflicting reinforcer expectancy. Addiction Biology, 18, 88-97.
Rose AK, Brown K, Field M, Hogarth L (2013). The contributions of value-based decision-making and attentional bias to alcohol-seeking following devaluation. Addiction, 108(7), 1241-1249. Abstract.  Author URL.
Hogarth L, Chase HW (2013). Vulnerabilities underlying human drug dependence: Goal valuation versus habit learning. In  (Ed) , 75-101.

2012

Rose AK, Hogarth L, Brown K (2012). ATTENTIONAL PROCESSES AND THE ABILITY OF ALCOHOL CUES TO TRIGGER HABIT-LIKE ALCOHOL-SEEKING BEHAVIOUR.  Author URL.
Hogarth L, Attwood AS, Bate HA, Munafò MR (2012). Acute alcohol impairs human goal-directed action. Biol Psychol, 90(2), 154-160. Abstract.  Author URL.
Hogarth L, Chase HW (2012). Evaluating psychological markers for human nicotine dependence: tobacco choice, extinction, and Pavlovian-to-instrumental transfer. Exp Clin Psychopharmacol, 20(3), 213-224. Abstract.  Author URL.
Hogarth L, Rose AK (2012). GOAL-DIRECTED CONTROL OVER ACTION SELECTION IN HUMANS IS IMPAIRED BY ACUTE ALCOHOL ADMINISTRATION AND ALCOHOL CUES.  Author URL.
Hogarth L (2012). Goal-directed and transfer-cue-elicited drug-seeking are dissociated by pharmacotherapy: evidence for independent additive controllers. J Exp Psychol Anim Behav Process, 38(3), 266-278. Abstract.  Author URL.
Hogarth L, Chase HW, Baess K (2012). Impaired goal-directed behavioural control in human impulsivity. Q J Exp Psychol (Hove), 65(2), 305-316. Abstract.  Author URL.
Jones A, Hogarth L, Christiansen P, Rose AK, Martinovic J, Field M (2012). Reward expectancy promotes generalized increases in attentional bias for rewarding stimuli. Q J Exp Psychol (Hove), 65(12), 2333-2342. Abstract.  Author URL.
Rose AK, Hogarth L, Brown K (2012). THE ROLE OF ATTENTION IN MEDIATING GOAL-DIRECTED ALCOHOL SEEKING.  Author URL.

2011

Field M, Hogarth L, Bleasdale D, Wright P, Fernie G, Christiansen P (2011). Alcohol expectancy moderates attentional bias for alcohol cues in light drinkers. Addiction, 106(6), 1097-1103. Abstract.  Author URL.
Haselgrove M, Hogarth L (2011). Clinical Applications of Learning Theory., Psychology Press. Abstract.
Norman NA, Hogarth L, Panlilio L, Shoaib M (2011). ESTABLISHING CONCURRENT CHOICE PROCEDURES WITH INTRAVENOUS NICOTINE AND SUCROSE IN RATS.  Author URL.
Norman N, Hogarth L, Panlilio L, Shoaib M (2011). ESTABLISHING CONCURRENT CHOICE PROCEDURES WITH INTRAVENOUS NICOTINE AND SUCROSE IN RATS.  Author URL.
Esfandiari A, Shoaib M, Hogarth L, Panlilio L (2011). ESTABLISHING PAVLOVIAN TO INSTRUMENTAL TRANSFER (PIT) WITH INTRAVENOUS NICOTINE AND SUCROSE IN RATS.  Author URL.
Craig M, Pennacchia A, Wright NR, Chase HW, Hogarth L (2011). Evaluation of un-medicated, self-paced alcohol withdrawal. PLoS One, 6(7). Abstract.  Author URL.
Chase HW, Hogarth L (2011). Impulsivity and symptoms of nicotine dependence in a young adult population. Nicotine Tob Res, 13(12), 1321-1325. Abstract.  Author URL.
Hogarth L, Chase HW (2011). Parallel goal-directed and habitual control of human drug-seeking: implications for dependence vulnerability. J Exp Psychol Anim Behav Process, 37(3), 261-276. Abstract.  Author URL.
Trick L, Hogarth L, Duka T (2011). Prediction and uncertainty in human Pavlovian to instrumental transfer. J Exp Psychol Learn Mem Cogn, 37(3), 757-765. Abstract.  Author URL.
Rose AK, Hogarth L (2011). THE ROLE OF CHOICE IN ALCOHOL DEPENDENCE.  Author URL.
Chase HW, Eickhoff SB, Laird AR, Hogarth L (2011). The neural basis of drug stimulus processing and craving: an activation likelihood estimation meta-analysis. Biol Psychiatry, 70(8), 785-793. Abstract.  Author URL.
Hogarth L (2011). The role of impulsivity in the aetiology of drug dependence: reward sensitivity versus automaticity. Psychopharmacology (Berl), 215(3), 567-580. Abstract.  Author URL.

2010

Hogarth L, Dickinson A, Duka T (2010). Selective attention to conditioned stimuli in human discrimination learning: Untangling the effect of outcome prediction, valence, arousal and uncertainty. In Mitchell CJ, Pelley MEL (Eds.) Attention and Associative Learning, Oxford University Press, 71-98.  Abstract.
Hogarth L, Dickinson A, Duka T (2010). The associative basis of cue-elicited drug taking in humans. Psychopharmacology (Berl), 208(3), 337-351. Abstract.  Author URL.

2009

Hogarth L, Dickinson A, Duka T (2009). Detection versus sustained attention to drug cues have dissociable roles in mediating drug seeking behavior. Exp Clin Psychopharmacol, 17(1), 21-30. Abstract.  Author URL.

2008

Hogarth L, Dickinson A, Austin A, Brown C, Duka T (2008). Attention and expectation in human predictive learning: the role of uncertainty. Q J Exp Psychol (Hove), 61(11), 1658-1668. Abstract.  Author URL.
Hogarth L, Dickinson A, Janowski M, Nikitina A, Duka T (2008). The role of attentional bias in mediating human drug-seeking behaviour. Psychopharmacology (Berl), 201(1), 29-41. Abstract.  Author URL.

2007

Duka T, Townshend J, Hogarth L, Stephens D (2007). Impaired learning of conditioned fear in alcoholics with a history of multiple detoxifications and in binge drinkers.  Author URL.
Hogarth L, Dickinson A, Wright A, Kouvaraki M, Duka T (2007). The role of drug expectancy in the control of human drug seeking.  Author URL.
Hogarth L, Dickinson A, Wright A, Kouvaraki M, Duka T (2007). The role of drug expectancy in the control of human drug seeking. J Exp Psychol Anim Behav Process, 33(4), 484-496. Abstract.  Author URL.

2006

Hogarth L, Dickinson A, Hutton SB, Bamborough H, Duka T (2006). Contingency knowledge is necessary for learned motivated behaviour in humans: relevance for addictive behaviour. Addiction, 101(8), 1153-1166. Abstract.  Author URL.
Hogarth L, Dickinson A, Hutton SB, Elbers N, Duka T (2006). Drug expectancy is necessary for stimulus control of human attention, instrumental drug-seeking behaviour and subjective pleasure. Psychopharmacology (Berl), 185(4), 495-504. Abstract.  Author URL.
Hogarth L, Duka T (2006). Human nicotine conditioning requires explicit contingency knowledge: is addictive behaviour cognitively mediated?. Psychopharmacology (Berl), 184(3-4), 553-566. Abstract.  Author URL.

2005

Hogarth L, Dickinson A, Duka T (2005). Explicit knowledge of stimulus-outcome contingencies and stimulus control of selective attention and instrumental action in human smoking behaviour. Psychopharmacology (Berl), 177(4), 428-437. Abstract.  Author URL.
Stephens DN, Ripley TL, Borlikova G, Schubert M, Albrecht D, Hogarth L, Duka T (2005). Repeated ethanol exposure and withdrawal impairs human fear conditioning and depresses long-term potentiation in rat amygdala and hippocampus. Biol Psychiatry, 58(5), 392-400. Abstract.  Author URL.
Hogarth L, Dickinson A, Hutton SB, Bamborough H, Duka T (2005). Stimulus control of human selective attention and instrumental avoidance behaviour depends upon explicit contingency knowledge.  Author URL.
Hogarth L, Dickinson A, Hutton SB, Duka T (2005). The control of human selective attention by cues associated with nicotine.  Author URL.

2003

Hogarth LC, Mogg K, Bradley BP, Duka T, Dickinson A (2003). Attentional orienting towards smoking-related stimuli. Behavioural Pharmacology, 14, 153-160.
Hogarth LC, Mogg K, Bradley BP, Duka T, Dickinson A (2003). Attentional orienting towards smoking-related stimuli. Behavioural Pharmacology, 14(2), 153-160. Abstract.
Hogarth L, Dickinson A, Duka T (2003). Discriminative stimuli that control instrumental tobacco-seeking by human smokers also command selective attention. Psychopharmacology (Berl), 168(4), 435-445. Abstract.  Author URL.

Lee_Hogarth Details from cache as at 2022-09-28 03:39:33

Refresh publications

External Engagement and Impact

Editorial responsibilities


Other

Public dissemination

British Science Festival, Birmingham, UK. From Pavlov to Present. 2010.


Workshops organised

Teaching

  • Module convenor for third year seminar Psychology of Addiction - PSY3437
  • Module convenor for third year research projects - PSY3401
  • Co-convernor for second year Biological Basis of Behaviour - PSY2304
  • Supervisor for BSc, MSc and PhD research projects
  • Organiser of BPS South West Undergraduate Psychology Conference 

Modules

2022/23


Supervision / Group

Postgraduate researchers

  • Alexandra Elissavet Bakou
  • Daniel Casey
  • Lorna Hardy
  • Hope Kent
  • Yihao Liu
  • Bella Magner-Parsons
  • Chloe Shuai

Back | Edit Profile